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. 2017 Jan 4;14(1):44. doi: 10.3390/ijerph14010044

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© 2017 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effects of long-term exposure to DEHP on the serum levels of thyroid-related hormones at 3 M and 6 M respectively. Groups of different doses of DEHP: 0 mg/kg/day, control group; 150 mg/kg/day, low-dose group; 300 mg/kg/day, middle-dose group; 600 mg/kg/day, high-dose group. Each bar represents the mean ± S.E.M (16/group). ^a Significantly different from the control at 3 M (p < 0.05); ^b Significantly different from the control at 3 M (p < 0.01); ^c Significantly different from the control at 6 M (p < 0.05); ^d Significantly different from the control at 6 M (p < 0.01). (A) TT3; (B) FT3; (C) TT4; (D) FT4; (E) TSH; (F) TSAb; (G) TRH. Radioimmunoassay: (A–E); Enzyme-linked immunoabsorbent assay: (F,G).