Table 4.
Disability Weights (DWs) of main and scenario analyses in comparison with GBD (Global Burden of Disease) 2013 DWs and comparability of health state descriptions.
| DiWIntox Ranking | DiWIntox | GBD Ranking | GBD 2013 | DiWIntox vs. GBD 2013 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Health States (HS) Used in DiWIntox (Ordered by Severity) | DWs (MA) | 95% UI (MA) | DWs (SA 1) | DWs (SA 2) | DWs (SA 3) | Health State Best Comparable to DiWIntox Health State | DWs | 95% UI | Comparability of HS Description ~ | Comparison of DiWIntox (MA) and GBD Results * | ||
| 1 | Mild Vision Disorder | 0.081 | 0.033–0.162 | 0.119 | / | 0.060 | 1 | Distance vision, mild impairment | 0.031 | 0.019–0.049 | moderate | Overlapping UIs |
| 2 | Deafness | 0.136 | 0.075–0.221 | 0.215 # | 0.215 # | 0.215 # | 6 | Hearing loss, complete | 0.215 | 0.144–0.307 | moderate | Overlapping UIs |
| 3 | Breast Cancer (Clinically disease-free stage without permanent sequelae) | 0.162 | 0.098–0.246 | 0.248 | / | 0.268 | 2 | Mastectomy | 0.036 | 0.020–0.057 | low | Not overlapping UIs |
| 4 | Problems of Alcohol Drinking | 0.189 | 0.122–0.274 | 0.277 | / | 0.316 | 7 | Alcohol use disorder: mild | 0.235 | 0.160–0.327 | high | Overlapping UIs; DWs within each other UI |
| 5 | Severe Asthma | 0.189 | 0.122–0.273 | 0.277 | / | 0.316 | 4 | Asthma, uncontrolled | 0.133 | 0.086–0.192 | high | Overlapping UIs; DW within each other UI |
| 6 | Chronic Low Back Pain | 0.203 | 0.134–0.288 | 0.290 | / | 0.337 | 10 | Low back pain: severe, with leg pain | 0.325 | 0.219–0.446 | moderate | Overlapping UIs |
| 7 | HIV/AIDS (seropositive, asymptomatic) | 0.208 | 0.139–0.293 | 0.296 | / | 0.346 | 3 | HIV/AIDS: receiving antiretroviral treatment | 0.078 | 0.052–0.111 | low | Not overlapping UIs |
| 8 | Mild Dementia | 0.223 | 0.152–0.309 | 0.309 | / | 0.367 | 12 | Dementia: mild | 0.377 | 0.252–0.508 | high | Overlapping UIs |
| 9 | Diabetes Mellitus (uncomplicated, poorly controlled) | 0.254 | 0.178–0.343 | 0.336 | / | 0.411 | / | n.a. | n.a. | n.a. | / | |
| 10 | Manifest Alcoholism | 0.312 | 0.223–0.413 | 0.380 | / | 0.482 | 11 | Alcohol use disorder: moderate | 0.373 | 0.248–0.508 | high | Overlapping UIs; DW within each other UI |
| 11 | Coronary Heart Disease, Severe Stable Angina | 0.347 | 0.248–0.458 | 0.404 | / | 0.521 | 5 | Angina pectoris: severe | 0.167 | 0.110–0.240 | high | Not overlapping UIs |
| 12 | Chronic Metallic Mercury Vapor Intoxication (moderate case) | 0.368 | 0.261–0.485 | 0.417 | 0.40 | 0.542 | / | n.a. | n.a. | n.a. | / | |
| 13 | Colorectal Cancer (Stage of diagnosis and primary therapy) | 0.368 | 0.261–0.485 | 0.418 | / | 0.543 | 8 | Cancer: diagnosis and primary therapy | 0.288 | 0.193–0.399 | low | Overlapping UIs; DW within each other UI |
| 14 | Stroke, moderate impairments | 0.431 | 0.300–0.569 | 0.458 | / | 0.608 | 9 | Stroke: long-term consequences, moderate plus cognition problems | 0.316 | 0.206–0.437 | high | Overlapping UIs; DW within each other UI |
| 15 | Severe Depression | 0.526 | 0.334–0.713 | 0.536 | / | 0.734 | 15 | Major depressive disorder: severe episode | 0.658 | 0.477–0.807 | high | Overlapping UIs; DW within each other UI |
| 16 | Delirium caused by excessive alcohol intake | 0.537 | 0.329–0.736 | 0.549 | / | 0.755 | 13 | Alcohol use disorder: severe | 0.570 | 0.396–0.732 | low | Overlapping UIs; DW within each other UI |
| 17 | Quadriplegia | 0.560 | 0.291–0.804 | 0.589 # | 0.82 # | 0.82 # | 14 | Spinal cord lesion at neck: treated | 0.589 | 0.415–0.748 | high | Overlapping UIs; DW within each other UI |
| 18 | Chronic Metallic Mercury Vapor Intoxication (severe case) | 0.588 | 0.194–0.907 | 0.664 | 0.80 | 0.941 | / | n.a. | n.a. | n.a. | / | / |
Abbreviations: DiWIntox: Disability Weight for Chronic Mercury Intoxication; GBD: Global Burden of Disease study; HS: health state; MA: main analysis; n.a.: not available; UI: uncertainty interval. *: Spearman’s Rho applied to the mean DiWIntox DWs of the main analysis and the mean GBD 2013 DWs: 0.77 (p-value < 0.001). #: Predefined value. ~: Comparability of health state descriptions used in DiWIntox and GBD 2013 was checked and documented in Table S1 (Supplementary Materials).