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. 2016 Aug 15;7(36):57498–57513. doi: 10.18632/oncotarget.11292

Figure 1. KB increases serum clearance of LPS and enhances hepatic LPS uptake in C57 BL/6 mice.

Figure 1

A. Mice were injected with normal saline (NS) or LPS (1 mg/kg) preincubated with NS or KB (3.6 mg/kg) at 37°C for 30 min. Serum levels of LPS and TNF-α were detected 4 h after injection (n = 3). B. Mice were injected with FITC-LPS (1 mg/kg) preincubated with NS or with KB (3.6 mg/kg). Serum and homogenates from liver, heart, spleen, lung and kidney were obtained at 1, 4, 8 and 24 h and FITC-LPS fluorescence was detected. *P < 0.05, **P < 0.01. C. C57 BL/6 mice were treated as in B. for 1 h, frozen liver tissue sections were prepared and FITC-LPS fluorescence was detected by confocal microscopy (objective×40). FITC-LPS fluorescence in whole liver tissues is expressed as means ± SD (n = 3). *P < 0.05 vs. FITC-LPS group.