Table 2. Characteristics of studies included in pooling SMD analysis.
| Author | Year | Country | Cancer Type | Study Design | Detection Assay | NOS Score | Cases | Controls | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Number | Mean | SD | Number | Mean | SD | |||||||
| Al-Haritby | 2010 | Saudi Arabia | CC | Retrospective case-control | ELISA | 4 | 60 | 19.44 | 8.46 | 60 | 5.45 | 2.73 |
| Alokail | 2013 | Saudi Arabia | BC | Retrospective case-control | ELISA | 6 | 56 | 18.9 | 1.2 | 53 | 15.2 | 1 |
| Aly | 2013 | Egypt | BC | Retrospective case-control | ELISA | 6 | 35 | 4.42 | 4.74 | 40 | 1.84 | 2.35 |
| Assiri | 2015 | Saudi Arabia | BC | Retrospective case-control | ELISA | 6 | 82 | 26.24 | 1.59 | 68 | 22.69 | 2.58 |
| Crusistomo(a)1 | 2016 | Portugal | BC | Retrospective case-control | ELISA | 7 | 30 | 11.6 | 7.31 | 29 | 7.51 | 3.6 |
| Crusistomo(b)1 | 2016 | Portugal | BC | Retrospective case-control | ELISA | 7 | 47 | 16.1 | 10.37 | 48 | 10.4 | 9.75 |
| Dalamaga | 2013 | Greece | BC | Retrospective case-control | ELISA | 6 | 102 | 11.2 | 6.4 | 102 | 7.7 | 4.85 |
| Danese1 | 2012 | Italy | CC | Retrospective case-control | ELISA | 6 | 40 | 8.96 | 3.42 | 40 | 4.97 | 1.07 |
| Diakowska | 2014 | Poland | EC | Retrospective case-control | ELISA | 6 | 41 | 8.99 | 3.21 | 60 | 7.5 | 2.7 |
| Gonullu1 | 2009 | Turkey | CC | Retrospective case-control | ELISA | 5 | 36 | 6.1 | 3.3 | 37 | 4.5 | 1.5 |
| Gunter1 | 2015 | United States | BC | Prospective case-cohort | Milliplex Human Adipokine Panel | 5 | 875 | 12.1 | 4 | 821 | 12.3 | 4.3 |
| Ho1 | 2012 | United States | CC | Prospective case-cohort | Milliplex Human Adipokine Panel | 6 | 457 | 12.8 | 4.81 | 834 | 12.3 | 4.3 |
| Hou | 2007 | China | BC | Retrospective case-control | ELISA | 6 | 80 | 26.35 | 5.36 | 50 | 23.32 | 4.75 |
| Joshi | 2014 | Korea | CC | Retrospective case-control | ELISA | 6 | 100 | 4.9 | 2.3 | 100 | 2.8 | 1.7 |
| Kang | 2007 | Korea | BC | Retrospective case-control | ELISA | 6 | 41 | 5.23 | 6.9 | 43 | 1.46 | 2 |
| Kumor | 2008 | Poland | CC | Retrospective case-control | ELISA | 4 | 36 | 6.79 | 2.41 | 25 | 3.6 | 1.08 |
| Liao1 | 2012 | Finland | RCC | Prospective nest case-control | ELISA | 8 | 273 | 9.27 | 2.73 | 273 | 9.28 | 2.83 |
| Tulubas | 2014 | Turkey | CC | Retrospective case-control | ELISA | 6 | 30 | 18.77 | 5.09 | 30 | 13.36 | 6.36 |
1
Data was recalculated by the method proposed by Hozo et al.
Abbreviations: SD = Standard Deviation; CI = Confidence Interval; ELISA = Enzyme-linked Immunosorbent Assay; NOS = Newcastle-Ottawa Scale; CI = Confidence Interval; BC = Breast Cancer; CC = Colorectal Cancer; EC = Esophageal Cancer