Table 3. Genotype frequencies of mTOR rs2295080 polymorphism in breast cancers and controls.
Model | Genotype | Case (n, %) | Control (n, %) | OR (95% CI) | P-value |
---|---|---|---|---|---|
Codominant | T/T | 351 (62.7%) | 345 (59.2%) | 1.00 | |
G/T | 197 (35.2%) | 212 (36.4%) | 0.91 (0.72–1.17) | ||
G/G | 12 (2.1%) | 26 (4.4%) | 0.45 (0.23–0.91) | 0.02 | |
Dominant | T/T | 351 (62.7%) | 345 (59.2%) | 1.00 | |
G/T–G/G | 209 (37.3%) | 238 (40.8%) | 0.86 (0.68–1.09) | 0.23 | |
Recessive | T/T–G/T | 548 (97.9%) | 557 (95.9%) | 1.00 | |
G/G | 12 (2.1%) | 26 (4.4%) | 0.47 (0.23–0.94) | 0.03 | |
Overdominant | T/T–G/G | 363 (64.8%) | 371 (63.6%) | 1.00 | |
G/T | 197 (35.2%) | 212 (36.4%) | 0.95 (0.75–1.21) | 0.68 | |
Allele | T | 899(80.3%) | 902 (77.4%) | 1.00 | |
G | 221(19.7%) | 264 (22.6%) | 0.84 (0.69–1.03) | 0.04 |