Table 1. Clinical features of the patients.
No | Gender | Age (ys) | Diagnos-is | IFN be-fore TKI (m) | Time to MMR (m) | Course of TKI | Time of cessation (m) | Number Of LSC (%) | BCR-ABL1 In MV | Relapse | Treatment |
---|---|---|---|---|---|---|---|---|---|---|---|
1 | Male | 21 | AP | No | 3 | IM 36 | 40 | 0.31 | 1.34 | N | |
2 | Male | 61 | CP | > 12 | 9 | IM 60 m+Ni 6 m | 27 | 0.16 | 0.76 | N | |
3 | Female | 68 | CP | No | 3 | IM 55 m | 4 | 0.45 | 3.45 | Y | Ni 300 mg bid |
4 | Female | 51 | CP | < 6 | 6 | IM 84 m | 2 | 0.66 | 1.96 | Y | IM 400 mg qd |
5 | Female | 20 | CP | No | 12 | IM 95 m | 22 | 0.76 | 0.85 | N | |
6 | Female | 15 | CP | > 12 | 12 | IM 84 m | 20 | 0.07 | 0.55 | N | |
7 | Female | 19 | AP | No | 15 | IM 96 m | 20 | 0.00 | 0.37 | N | |
8 | Female | 29 | CP | No | 6 | IM 66 m | 18 | 0.55 | 1.32 | N | |
9 | Female | 16 | CP | No | 6 | IM 92 m | 14 | 0.02 | 1.76 | Y | Refuse |
10 | Male | 20 | CP | No | 6 | IM 78 m | 10 | 0.03 | 1.14 | Y | Refuse |
11 | Female | 34 | CP | No | 6 | IM 72 m | 13 | 0.30 | 2.98 | Y | Refuse |
12 | Male | 28 | CP | No | 18 | IM 103 m | 1 | 0.09 | 3.82 | Y | IM 400 mg qd |
13 | Female | 34 | CP | No | 12 | IM 40 m | 5 | 0.17 | 0.94 | Y | Refuse |
14 | Female | 51 | CP | No | 6 | IM 102 m | 6 | 0.44 | 0.87 | Y | IM400 mg qd |
15 | Male | 14 | CP | No | 15 | IM 78 m | 11 | 0.41 | 2.16 | N | |
16 | Male | 29 | CP | > 12 | 24 | IM 36 m+Ni 18 m | 11 | 0.00 | 0.98 | N | |
17 | Male | 20 | CP | No | 9 | IM 64 m | 3 | 0.07 | 1.35 | Y | IM 400 mg qd |
18 | Female | 60 | CP | No | 3 | IM 77 m | 4 | 0.19 | 0.87 | Y | IM 400 mg qd |
19 | Female | 46 | CP | > 12 | 6 | IM 48 m+Ni 29 m | 9 | 0.08 | 1.32 | N | |
20 | Male | 48 | CP | No | 6 | IM 24 m+Ni 33 m | 7 | 0.13 | 0.83 | N | |
21 | Female | 23 | CP | No | 7 | IM 62 m | 9 | 0.34 | 1.78 | N | |
22 | Female | 25 | CP | < 6 | 9 | IM 47 m | 24 | 0.41 | 1.54 | N |
Note: According to their Sokal scores, patients 13–15 were classified as high-risk patients, patients 2–12 were classified as intermediate-risk patients, and the rest were classified as low-risk patients.