Table 1. Basal characteristics.
| Variable | Derivation set (N=235) | Validation set (N=84) | P Value |
|---|---|---|---|
| Pre-SR | |||
| Age, y | 52.1+-10.2 | 52.6+-10.7 | 0.702 |
| Gender | 0.762 | ||
| Male | 204 (86.8) | 74 (88.1) | |
| Female | 31 (13.2) | 10 (11.9) | |
| HBeAg | 0.407 | ||
| Positive | 67 (28.5) | 28 (33.4) | |
| Negative | 168 (71.5) | 56 (66.6) | |
| Child-Pugh stage | 0.951 | ||
| A | 232 (98.7) | 83 (98.8) | |
| B | 3 (1.3) | 1 (1.2) | |
| BCLC-stage | 0.977 | ||
| A | 65 (27.7) | 24 (28.6) | |
| B | 143 (60.9) | 50 (59.5) | |
| C | 27 (11.4) | 10 (11.9) | |
| Aspartate aminotransferase, IU/L | 41.1+-24.4 | 41.2+-30.4 | 0.974 |
| Creatinine, umol/L | 73.6+-15.5 | 73.9+-16.3 | 0.875 |
| neutrophil, 10 9/L | 3.3+-1.5 | 3.5+-1.6 | 0.456 |
| lymphocyte, 10 9/L | 1.8+-0.7′ | 1.9+-0.8 | 0.321 |
| Pathology | |||
| Cirrhosis | 0.941 | ||
| Yes | 195 (83.0) | 70 (83.3) | |
| No | 40 (17.0) | 14 (16.7) | |
| Tumor factors | |||
| Vascular invasion | 0.708 | ||
| No | 110 (46.8) | 35 (41.7) | |
| Microvascular invasion | 98 (41.7) | 39 (46.4) | |
| Macrovascular invasion | 27 (11.5) | 10 (11.9) | |
| Tumor diameter, cm | 6.5+-4.0 | 6.6+-4.2 | 0.881 |
| Tumor number | 0.375 | ||
| single nodule | 139 (59.1) | 45 (53.6) | |
| Multiple nodules | 96 (40.9) | 39 (46.4) | |
| Capsule | 0.905 | ||
| Complete | 186 (79.1) | 67 (79.8) | |
| Incomplete | 49 (20.9) | 17 (20.2) | |
| Edmonson-Steiner classification | 0.636 | ||
| I/II | 144 (61.3) | 54 (64.3) | |
| III/IV | 91 (38.7) | 30 (35.7) | |
| lymph nodemetastasis | 0.442 | ||
| Yes | 7 (3.0) | 4 (4.8) | |
| No | 228 (97.0) | 80 (95.2) | |
| Surgical factors | |||
| Portal vein tumor thrombus | 0.719 | ||
| Yes | 22 (9.4) | 9 (10.7) | |
| No | 213 (90.6) | 75 (89.3) | |
| Clamping time, min | 0.549 | ||
| Yes | 103 (43.8) | 44 (52.4) | |
| No | 132 (56.2) | 40 (47.6) | |
| Blood transfusion | 0.69 | ||
| Yes | 32 (13.6) | 10 (11.9) | |
| No | 203 (86.4) | 74 (88.1) | |
| Pre-pTACE | |||
| Alphae-fetoprotein, ng/mL | 0.762 | ||
| <200 | 191 (81.3) | 67 (79.8) | |
| >=200 | 44 (18.7) | 17 (20.2) | |
| Child-Pugh stage | 0.362 | ||
| A | 199 (83.8) | 74 (88.1) | |
| B | 38 (16.2) | 10 (11.9) | |
| HBV-DNA level, IU/mL | 0.656 | ||
| <=10 4 | 156 (66.4) | 58 (69.0) | |
| >10 4 | 79 (33.6) | 26 (31.0) | |
| Aspartate aminotransferase, IU/L | 49.0+-40.2 | 50.1+-42.9 | 0.834 |
| Creatinine, umol/L | 69.4+-17.2 | 71.3+-21.2 | 0.396 |
| neutrophil, 10 9/L | 3.8+-6.7 | 4.7+-10.9 | 0.383 |
| lymphocyte, 10 9/L | 1.5+-0.7 | 1.5+-0.6 | 0.51 |
| Platelets, 10 9/L | 146.3+-60.1 | 139.6+-50.3 | 0.36 |