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. 2016 Aug 5;7(36):58315–58330. doi: 10.18632/oncotarget.11089

Figure 1. ω-3 PUFAs intake prevents AOM/DSS-induced colorectal cancer.

Figure 1

A. Tumor induction protocol. Mice were injected with AOM on day 1 followed by three rounds of DSS treatment. After 1 week, 2.5% DSS was administered in the drinking water for 5 days, followed by 16 days of tap water in sterile. This cycle was repeated twice (5 days of 2.5% DSS followed by a 16 days recovery period and 5 days of 2.5% DSS). Mice were terminated at week 11 after injection of AOM. B. Body weight changes in mice fed with different diets. Values are means ± SEM. C. Photographs showing colons with tumors from mice fed with the control diet (left) and mice fed with the diet supplemented with ω-3 PUFAs (right). D. Representative hematoxylin and eosin stain of colorectal tumor.