Figure 2. GHK-Cu downregulated the release of TNF-α and IL-6 in LPS-induced RAW 264.7 cells activation.

TNF-α and IL-6 levels in culture supernatants were determined by ELISA. These data showed that cells that were pretreated with 10 μM GHK-Cu exhibited significantly decreased secretion of TNF-α and IL-6. The data represent the means ± SD (n = 3). *p < 0.05, statistically significant difference. CTL, control.