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. 2016 Aug 10;7(36):58405–58417. doi: 10.18632/oncotarget.11168

Figure 8. MAPKs and NF-κB signaling pathway is involved in the anti-inflammatory effect of GHK-Cu.

Figure 8

A. Phosphorylation of NF-κB p65 at Ser536, p38 MAPK, ERK1/2, and JNK1/2 was assessed by western blotting of lung homogenates with a phosphorylation site-specific antibody. NF-κB p65 and p38 MAPK, JNK1/2, and ERK1/2 were used as loading controls. B. The blots were subjected to a densitometric analysis and relative quantification. The values are the means ± SD after normalization for NF-κB p65, p38 MAPK, JNK1/2, and ERK1/2 (n = 3). A representative blot is shown for each condition. *p < 0.05, statistically significant difference.