Table 4. Clinical trials for current oncolytic virotherapy.
| Virus | Name | Modification | Phase | References* |
|---|---|---|---|---|
| Herpesvirus | T-VEC | ICP34.5(-), GM-CSF expression | 2 | NCT02658812 |
| G207 | ICP34.5(-), ICP6(-) | 1/2 | NCT00028158 | |
| Adenovirus | CG0070 | E2F promoter, GM-CSF expression | 3 | NCT02365818 |
| ICOVIR-5 | E2F promoter, E1A(-) | 1 | NCT01864759 | |
| OBP-031 | hTERT promoter | 1/2 | NCT02293850 | |
| N/A | IL-12 expression | 1 | NCT00406939 | |
| Retrovirus | Toca511 | Cytosine deaminase expression | 1 | NCT01470794 |
| Vaccinia virus | JX-594 | GM-CSF expression | 1 | NCT01380600 |
| Vesicular stomatitis virus | VSV-hIFNβ | Interferon-β expression | 1 | NCT01628640 |
*
NCT number is the identifier number on ClinicalTrials.gov.