Table III.
Characteristics of the Intention-to-Treat Participants at Randomization*
| Intervention N=125 | Usual Care N=122 | p-value | |
|---|---|---|---|
| Age (yrs.) | 0.99 | ||
| 6 to 17 | 56 (44.8%) | 54 (44.3%) | |
| 18 to 69 | 69 (55.2%) | 68 (55.7%) | |
| Sex: | 0.42 | ||
| Female | 73 (58.4%) | 64 (52.5%) | |
| Male | 52 (41.6%) | 58 (47.5%) | |
| Race/ethnicity: | 0.11 | ||
| Hispanic | 67 (55.4%) | 72 (61.0%) | |
| Black (non-Hispanic) | 47 (38.8%) | 45 (38.1%) | |
| White (non-Hispanic) | 7 (5.79%) | 1 (0.85%) | |
| Borough: | 0.60 | ||
| Bronx | 89 (71.8%) | 81 (66.4%) | |
| Manhattan | 29 (23.4%) | 30 (24.6%) | |
| Brooklyn | 4 (3.23%) | 7 (5.74%) | |
| Queens | 2 (1.61%) | 4 (3.28%) | |
| Body Mass Index (kg/m2) | 28.9 (8.75) | 27.8 (8.72) | 0.36 |
| Asthma symptoms (days past 2 weeks) | 2.34 (3.00) | 1.87 (2.59) | 0.19 |
| Rescue (albuterol) inhaler (days past 2 weeks) | 2.10 (2.77) | 1.72 (2.74) | 0.28 |
| Awakened with asthma symptoms (days past 2 weeks) | 1.17 (2.98) | 0.79 (2.19) | 0.25 |
| ACT (n=175) | 19.5 (4.14) | 20.2 (3.94) | 0.23 |
| Childhood ACT (n=69) | 21.9 (4.74) | 22.7 (3.60) | 0.45 |
| eNO (ppb) | 28.8 (25.5) | 27.0 (23.0) | 0.61 |
| Total IgE (kU/L) | 416 (556) | 517 (632) | 0.37 |
| FEV1/FVC ratio ‡ | 0.76 (0.09) | 0.78 (0.11) | 0.30 |
| FEV1 (% predicted) Pre ‡ | 85.4 (18.6) | 84.9 (18.1) | 0.84 |
| FEV1 (% predicted) Post ‡ | 90.4 (22.0) | 90.4 (17.3) | 0.99 |
| FEV1 (% predicted) Change ‡ | 6.79 (9.97) | 7.53 (10.2) | 0.57 |
| Reversibility 10 percent: Yes | 36 (29.0%) | 32 (26.4%) | 0.65 |
| Control Level: | |||
| 1 | 69 (55.6%) | 62 (51.2%) | 0.73 |
| 2 | 11 (8.87%) | 11 (9.09%) | |
| 3 | 17 (13.7%) | 23 (19.0%) | |
| 4 | 27 (21.8%) | 25 (20.7%) | |
| Control level mean | 2.02 (1.26) | 2.09 (1.24) | 0.64 |
| Treatment step at Randomization (categorical): | 0.10 | ||
| 1 | 2 (1.61%) | 3 (2.50%) | |
| 2 | 17 (13.7%) | 14 (11.7%) | |
| 3 | 22 (17.7%) | 21 (17.5%) | |
| 4 | 19 (15.3%) | 27 (22.5%) | |
| 5 | 14 (11.3%) | 3 (2.50%) | |
| 6 | 50 (40.3%) | 52 (43.3%) | |
| Treatment step at randomization (Continuous): | 4.42 (1.56) | 4.41 (1.57) | 0.96 |
| Juniper Mini Asthma Quality of Life Score + | 5.03 (1.32) | 5.57 (1.26) | 0.02 |
| Reported smokers in home: Yes | 43 (34.4%) | 33 (27.0%) | 0.27 |
| “Spend a lot of time with someone who smokes” | 41 (33.3%) | 30 (25.6%) | 0.24 |
| Cat/dog/pet rodent in your home now or 6 months prior: Yes | 24 (35.3%) | 21 (34.4%) | 0.99 |
*
Values are count (percent) or mean (standard deviation).
‡
FEV1 Denotes forced expiratory volume in one second, and FVC denotes forced vital capacity.
+
Higher score denotes better quality of life.