Table 2. Association of the KCNJ10:c.986T>C genotypes with cerebellar dysfunction.
| Genotype KCNJ10:c.986T>C | T/T | C/T | C/C |
|---|---|---|---|
| Malinois cases (families 1–4, MA152) | — | — | 7 |
| Malinois cases (families 5 and 6, six isolated dogs) | 9 | 3 | — |
| Malinois controls | 176 | 43 | — |
| Groenendael controls | 25 | — | — |
| Laekenois controls | 2 | — | — |
| Tervueren controls | 33 | 1a | — |
| Control dogs from other breedsb | 486 | — | — |
a
This Tervueren dog had Malinois parents.
b
These dogs were specifically genotyped for the KCNJ10:c.986T>C variant. The genome sequences of 140 independent control dogs were also homozygous T/T at this variant. Therefore, the number of control dogs totals 626.