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. 2016 Dec 28;7(2):731–739. doi: 10.1534/g3.116.037879

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Copyright © 2017 Grainger et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Genome-wide QTL analysis for carotid lesion sizes in the F2 population. Chromosomes 1 through 20 are represented numerically on the x-axis. y-axis represents LOD score. The horizontal dashed line denotes the genome-wide threshold for suggestive linkage, which was determined by 1000 permutations. Top panel: a genome-wide scan using untransformed carotid lesion data performed with the nonparametric algorism; bottom panel: a genome-wide scan using log2-transformed carotid lesion data performed with the parametric mode. LOD, logarithm of the odds; QTL, quantitative trait locus.