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. 2017 Feb 7;12(2):e0171212. doi: 10.1371/journal.pone.0171212

Table 1. Parameters of the extended GM model and their values fitted for reproducing Wnt/DKK hair follicle patterning.

Notation Value Explanation [measure units]
ρ 0.05 Empirical parameter characterizing strength of Wnt-induced Wnt and DKK production [a.u.].
μu 0.003 Wnt degradation rate [s−1]
μv 0.008 DKK degradation rate [s−1]
D 100 Free diffusion coefficient [μm2s−1]
k1 7.8 Adsorption rate constant [μM−1s−1]
k−1 0.2 Desorption rate constant [s−1]
w0 10 Volume binding site density [μM]
u(t) 0–0.1 Non-bonded WNT fraction [μM]
u(t) + w0w(t) 0–50 Total WNT fraction [μM]
v(t) 0–50 DKK concentration [μM]
ρv 0.02–0.03 Permanent independent production of DKK [μMs−1]