Table 2. Peptides with motifs are enriched in the set of immunoreactive peptides (confusion table, Chi-Square test and Wilcoxon test).

Between brackets the proportions per row and per column are given.

Motif 1. PxxTQE	Without Motif	With Motif
Not immunoreactive	811805 (100%, 97.49%)	2 (0%, 6.9%)
Immunoreactive*	20875 (99.87%, 2.51%)	27 (0.13%, 93.1%)
χ-square p-value: 1.49e-205
Wilcoxon p-value: 2.227e-20
Motif 2. DGxDK	Without Motif	With Motif
Not immunoreactive	811805 (100%, 97.49%)	2 (0%, 4.44%)
Immunoreactive*	20859 (99.79%, 2.51%)	43 (0.21%, 95.56%)
χ-square p-value: 0
Wilcoxon p-value: 5.104e-31
Motif 3. Qx(S|T)N(L|I)D	Without Motif	With Motif
Not immunoreactive	811805 (100%, 97.49%)	2 (0%, 11.11%)
Immunoreactive*	20886 (99.92%, 2.51%)	16 (0.08%, 88.89%)
χ-square p-value: 8.12e-114
Wilcoxon p-value: 3.061e-13

* Immunoreactive peptides defined as peptides with adj. P-value < 0.05 in peptide microarray.