TABLE 1.
Skeletal muscle cytokine profile on poststroke d 7
| Cytokine/chemokine | Position | RAMT− | RAMT+ | Fold change |
|---|---|---|---|---|
| CINC-1 | A3, A4 | 0.17 | 0.2 | 1.21 |
| CINC-2α/β | A5, A6 | ND | ND | — |
| CINC-3 | A7, A8 | 0.03 | 0.02 | 0.61 |
| CNTF | A9, A10 | 0.5 | 0.67 | 1.32 |
| Fractalkine | A11, A12 | 0.23 | 0.33 | 1.45 |
| GM-CSF | A13, A14 | 0.03 | 0.04 | 1.41 |
| sICAM-1 | A15, A16 | 0.73 | 0.84 | 1.15 |
| IFN-γ | A17, A18 | ND | ND | — |
| IL-1α | B3, B4 | 0.29 | 0.43 | 1.47 |
| IL-1β | B5, B6 | 0.05 | ND | — |
| IL-1ra | B7, B8 | 0.05 | 0.12 | 2.25 |
| IL-2 | B9, B10 | 0.16 | 0.34 | 2.16 |
| IL-3 | B11, B12 | 0.22 | 0.36 | 1.61 |
| IL-4 | B13, B14 | 0.05 | ND | — |
| IL-6 | B15, B16 | ND | ND | — |
| IL-10 | B17, B18 | 0.14 | 0.17 | 1.24 |
| IL-13 | C3, C4 | 0.14 | 0.22 | 1.65 |
| IL-17 | C5, C6 | 0.12 | 0.19 | 1.61 |
| IP-10/CXCL10 | C7, C8 | 0.04 | 0.03 | 0.73 |
| LIX | C9, C10 | 0.12 | 0.22 | 1.94 |
| L-Selectin | [11C], C12 | 0.52 | 0.65 | 1.24 |
| MIG | [13C], C14 | 0.19 | 0.15 | 0.8 |
| MIP-1α | C15, C16 | 0.07 | 0.08 | 1.12 |
| MIP-3α | C17, C18 | ND | ND | — |
| RANTES | D3, D4 | 0.15 | 0.25 | 1.69 |
| Thymus chemokine | D5, D6 | 0.8 | 0.88 | 1.1 |
| TIMP-1 | D7, D8 | 0.04 | 0.07 | 1.55 |
| TNF-α | D9, D10 | ND | ND | — |
| VEGF | D11, D12 | 0.3 | 0.29 | 0.97 |
ND, not detected. Italicized cytokines were validated by immunohistochemistry (Fig. 7B, C).