Table 2. Primary and secondary study outcomes by treatment group.
| Menstrual outcomes | Moxibustion group, n = 75 | Control group, n = 72 | Unadjusted difference (95%CI) | Unadjusted P-value | Adjusted difference (95%CI) | Adjusted P-value |
|---|---|---|---|---|---|---|
| Pain intensity measured by VAS | ||||||
| 0 month | 6.38±1.28 | 6.41±1.29 | -0.04 (-0.45, 0.38) | .87 | -0.04 (-0.46, 0.39) | .86 |
| 1 month | 5.45±1.34 | 4.69±1.21 | 0.75 (0.34, 1.71) | <.0001 | 0.75 (0.33, 1.17) | <.0001 |
| 2 month | 4.34±1.22 | 3.73±1.24 | 0.61 (0.21, 1.01) | <.0001 | 0.62 (0.21, 1.03) | <.0001 |
| 3 month | 2.54±1.41 | 2.47±1.29 | 0.07 (-0.37, 0.51) | .75 | 0.07 (-0.38, 0.52) | .76 |
| 4 month | 2.70±1.54 | 2.84±1.46 | -0.14 (-0.63, 0.35) | .57 | -0.12 (-0.61, 0.38) | .65 |
| 5 month | 2.81±1.53 | 3.33±1.35 | -0.51 (-0.98, -0.42) | .03 | -0.46 (-0.94, 0.01) | .06 |
| 6 month | 3.08±1.49 | 4.01±1.21 | -0.93 (-1.38, -0.49) | <.0001 | -0.87 (-1.32, -0.42) | <.0001 |
| Menstrual pain duration (days) | ||||||
| 0 month | 5.38±2.79 | 5.63±2.88 | -0.24 (-1.16, 0.69) | .61 | -0.34 (-1.28, 0.60) | .47 |
| 1 month | 1.81±1.02 | 1.83±1.51 | -0.03 (-0.45, 0.39) | .89 | -0.10 (-0.52, 0.32) | .65 |
| 2 month | 1.52±0.98 | 1.61±1.67 | -0.09 (-0.54, 0.35) | .68 | -0.14 (-0.59, 0.31) | .53 |
| 3 month | 1.29±1.06 | 1.43±1.70 | -0.14 (-0.60, 0.32) | .55 | -0.18 (-0.65, 0.29) | .44 |
| 4 month | 1.05±0.92 | 1.18±1.52 | -0.13 (-0.54, 0.28) | .52 | -0.17 (-0.59, 0.24) | .41 |
| 5 month | 1.11±0.89 | 1.33±1.48 | -0.23 (-0.62, 0.17) | .27 | -0.25 (-0.66, 0.15) | .22 |
| 6 month | 1.23±0.89 | 1.63±1.47 | -0.40 (-0.79, 0.00) | .05 | -0.43 (-0.83, -0.03) | .04 |
| Menstrual symptom intensity score measured CMSS | ||||||
| 0 month | 16.01±7.96 | 15.78±6.90 | -0.24 (-2.20, 2.67) | .85 | 0.26 (-2.22, 2.73) | .84 |
| 1 month | 14.07±7.92 | 12.79±6.13 | 1.28 (-1.04, 3.59) | .28 | 1.28 (-1.07, 3.64) | .28 |
| 2 month | 10.85±6.49 | 10.76±6.24 | 0.09 (-1.99, 2.17) | .93 | 0.03 (-2.08, 2.14) | .98 |
| 3 month | 6.24±4.99 | 7.65±5.26 | -1.41 (-3.08, 0.26) | .10 | -1.53 (-3.23, 0.16) | .08 |
| 4 month | 6.12±4.95 | 7.71±5.25 | -1.59 (-3.25, -0.07) | .06 | -1.66 (-3.35, -0.03) | .05 |
| 5 month | 5.21±4.55 | 8.58±5.47 | -3.37 (-5.01, -1.73) | <.0001 | -3.45 (-5.12, -1.79) | <.0001 |
| 6 month | 4.84±3.19 | 9.78±5.38 | -4.94 (-6.51, -3.37) | < .0001 | -4.98 (-6.58, -3.39) | <.0001 |
| Menstrual symptom duration score measured CMSS (days) | ||||||
| 0 month | 20.64±11.07 | 19.83±9.22 | 0.81 (-2.52, 4.14) | .63 | 0.58 (-2.80, 3.96) | .74 |
| 1 month | 16.37±8.85 | 15.53±7.82 | 0.85 (-1.88, 3.57) | .54 | 0.69 (-2.08, 3.46) | .69 |
| 2 month | 12.56±8.51 | 12.61±7.53 | -0.05 (-2.67, 2.57) | .97 | -0.20 (-2.87, 2.47) | .88 |
| 3 month | 7.03±5.97 | 8.78±6.30 | -1.75 (-3.75, 0.25) | .09 | -1.98 (-4.00, 0.05) | .06 |
| 4 month | 6.44±5.48 | 8.25±5.75 | -1.81 (-3.64, 0.02) | .05 | -1.95 (-3.81, -0.09) | .04 |
| 5 month | 4.91±3.88 | 8.10±5.35 | -3.19 (-4.71, -1.67) | <.0001 | -3.28 (-4.82, -1.74) | <.0001 |
| 6 month | 4.51±3.73 | 9.40±5.36 | -4.89 (-6.40, -3.39) | <.0001 | -4.99 (-6.52, -3.47) | <.0001 |