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. 2017 Jan 8;9(1):5. doi: 10.3390/cancers9010005

Figure 1.

Figure 1

Schematic of DNA compaction levels facilitated by nucleosomes. Left: (A) DNA wound around the histone octamer, forming a nucleosome; (B) Nucleosomes aggregated into chromatin fibres, which compile into higher order three-dimensional loops and domains; (C) Chromatin fibres assembling into chromosomes. Right: indication of the scale of each successive structures compaction.