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. 2017 Feb;58(2):781–796. doi: 10.1167/iovs.16-20611

Figure 3.

Figure 3

Bone morphogenetic protein-7 application blocks TGFβ2-mediated α-SMA. Immunofluorescence confocal microscopy of control explants at 48 hours showed low levels of basal cytoplasmic α-SMA immunoreactivity (A), while explants treated with TGFβ2 exhibited strong immunoreactivity for α-SMA, colabeling to stress fibers (B). Cotreatment with BMP-7 (5 ng/ml) and TGFβ2 (C) and treatment with BMP-7 alone (D) showed no difference in α-SMA labeling compared to control explants. Images are representative of 3 independent experiments. Scale bar: 50 μm.