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. 2017 Feb 2;10:591–596. doi: 10.2147/OTT.S124097

Table 1.

Baseline characteristics of the Western European cohort

Characteristic nab-P + Gem
(n=38)
Gem
(n=38)
All patients in Western Europe (n=76) ITT population
(N=861)*
Age, median (range), years 59.5 (37–77) 66.0 (42–80) 63.0 (37–80) 63.0 (27–88)
 ≥65 years, % 29 61 45 42
Male, % 53 39 46 58
KPS, %
 90–100 74 82 78 60
 70–80 24 18 21 40
Primary tumor location, %
 Head 39 27a 33 43
 Body 47 49a 48 31
 Tail 13 24a 19 25
Site(s) of metastasis, %
 Liver 87 84 86 84
 Lung 24 45 34 39
No of metastatic sites, %
 1 8 8 8 6
 2 53 47 50 47
 ≥3 39 45 42 46
Previous Whipple, % 0 5 3 7
Biliary stent, % 8 8 8 17

Notes:

a

Evaluable n=37.

*

From N Engl J Med, Von Hoff DD, Ervin T, Arena FP, et al, Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine, 69, 1691–1703. Copyright © (2013) Massachusetts Medical Society. Reprinted with permission from Massachusetts Medical Society.8

Abbreviations: Gem, gemcitabine; ITT, intention-to-treat; KPS, Karnofsky performance status; nab-P, nab-paclitaxel.