Table 1. Clinicopathological factors related to the development of bone metastasis (BM) in breast cancer (BC) patients.

Risk Factor	Association	References
Age	Unknown/Conflicting results	[4, 39–41]
Menopausal status	Unknown/Conflicting results	[3, 41]
BMI	No relationship	[45]
Histological type	No relationship (surrogate marker for intrinsic subtype)	[39, 40, 48, 49]
Grade	Inverse/Conflicting results	[41, 48]
Tumour size	No relationship	[39, 50, 51]
Lymph node (LN) involvement	Might contribute, not major	[39]