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. Author manuscript; available in PMC: 2018 Feb 15.
Published in final edited form as: Eur J Med Chem. 2016 Oct 27;127:793–809. doi: 10.1016/j.ejmech.2016.10.059

Fig. 4. Inhibition of translation of luciferase mRNA in rabbit reticulocyte extract assays.

Fig. 4

Left panel, SAP A14C inhibition of luciferase translation in rabbit reticulocyte lysate assay. Right panel, Luciferase translation was rescued from 10 nM SAP A14C by compound 2 with an apparent IC50 of 13 nM, a 3 nM stoichiometric excess relative to saporin concentration.