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. Author manuscript; available in PMC: 2018 Feb 15.
Published in final edited form as: J Immunol. 2017 Jan 13;198(4):1460–1473. doi: 10.4049/jimmunol.1601415

Fig. 1. Memory compartment clonal abundance is comparable between healthy and MG repertoires.

Fig. 1

(A) The rank-abundance distribution of memory compartment heavy chain clones with clone size (y-axis) as a percent of the repertoire against the size rank of the clone on a log10 scale (x-axis). Each dark line represents the estimated clonal abundance curve for a single subject, with shaded areas representing 95% confidence intervals derived via bootstrap (2,000 realizations). Subject status is denoted by HD, AChR (AChR-MG), and MuSK (MuSK-MG).

(B) Evenness at diversity order q=4 of the heavy chain memory compartment clone size distributions. Each point represents the estimated evenness score for a subject from the clonal abundance distributions in panel A. The vertical shading represents the standard deviation of the mean evenness scores and the horizontal bar represents the mean of the mean evenness scores. HD vs AChR-MG t-test p=0.100; HD vs MuSK-MG t-test p=0.382.