Table 1.
General baseline characteristics by sex for FACT participants with PTHM measures
| All Participants (n = 324) | Males (n = 162) | Females (n = 162) | ||
|---|---|---|---|---|
| Characteristic | Median (IQR) | Median (IQR) | Median (IQR) | Pa |
| Age (years) | 39 (34–44) | 42 (36–46) | 37 (31–42) | <0.01 |
| BMI (kg/m2)b | 19.2 (17.7–21.3) | 18.7 (17.7–20.3) | 20.0 (17.9–22.5) | <0.01 |
| Blood Arsenic (µg/L) | 8.7 (6.0–12.4) | 9.5 (6.5–12.4) | 7.9 (5.3–12.4) | 0.04 |
| bSe (µg/L) | 134 (122–149) | 135 (123–151) | 132 (120–146) | 0.16 |
| RBC Folate (nmol/L)c | 451 (363–603) | 434 (362–572) | 461 (364–607) | 0.34 |
| Plasma Folate (nmol/L) | 12 (9–17) | 12 (8–16) | 13 (10–18) | 0.10 |
| Plasma Vitamin B12 (pmol/L) | 215 (153–319) | 217 (154–296) | 213 (153–338) | 0.49 |
| Plasma Choline (µmol/L) | 11.0 (9.8–13.1) | 11.9 (10.4–13.3) | 10.7 (9.0–12.4) | <0.01 |
| Plasma Betaine (µmol/L) | 42.8 (33.9–52.0) | 47.0 (40.2–57.5) | 37.3 (28.9–44.9) | <0.01 |
| Plasma Hcys (µmol/L) | 11.4 (8.8–15.5) | 14.2 (11.1–17.4) | 9.3 (7.4–12.0) | <0.01 |
| H3K36me2d, relative % of total H3 | 1.44 (1.26–1.72) | 1.45 (1.26–1.76) | 1.43 (1.26–1.70) | 0.66 |
| H3K36me3e, relative % of total H3 | 1.61 (1.32–1.88) | 1.56 (1.26–1.84) | 1.63 (1.37–1.94) | 0.10 |
| H3K79me2f, relative % of total H3 | 1.27 (1.03–1.76) | 1.26 (1.05–1.74) | 1.29 (1.01–1.85) | 0.96 |
| Folate Deficientg (%) | 23.2 | 28.4 | 17.9 | 0.03 |
| Vitamin B12 Deficienth (%) | 24.4 | 24.1 | 24.7 | 0.90 |
| HHcys (%)i | 40.7 | 62.4 | 19.1 | <0.01 |
| Ever Smoked Cigarette (%) | 28.8 | 56.2 | 1.2 | <0.01j |
| Ever Used Betel Nut (%) | 26.9 | 29.0 | 24.8 | 0.40 |
| Education > 5 years (%) | 22.5 | 21.0 | 24.1 | 0.51 |
| Own TV (%) | 38.3 | 32.7 | 43.8 | 0.04 |
a
P was from Wilcoxon rank-sum test and Chi square test for sex difference for continuous and categorical variables, respectively
b
Whole sample, n = 315; Men, n = 160; Women, n = 155
c
Whole sample, n = 250; Men, n = 125 ; Women, n = 125
d
Whole sample, n = 318; Men, n = 159; Women, n = 159
e
Whole sample, n = 306; Men, n = 154; Women, n = 152
f
Whole sample, n = 321; Men, n = 162; Women, n = 159
g
Plasma folate < 9 nmol/L
h
Plasma vitamin B12 <151 pmol/L
i
Plasma Hcys ≥ 13 µmol/L
j
P was from Fisher’s exact test, since there were only two female smokers