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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Blood Rev. 2016 Sep 2;31(1):77–84. doi: 10.1016/j.blre.2016.08.006

Table 2. DOAC reversal strategies.

Strategy Example
Removal Activated charcoal
Hemodialysis (dabigatran only)
Bypassing Prothrombin complex concentrate
Activated prothrombin complex concentrate
Recombinant factor VIIa
Sequestration Idarucizumab (dabigatran only)
Andexanet alfa (factor Xa inhibitors)
Ciraparantag