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. 2017 Feb 8;8:55. doi: 10.3389/fphys.2017.00055

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Copyright © 2017 Liu, Huang, Wu, Xu, Sun, Zhang, Chen and Gao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Circulating microRNAs expression profile was different between acute mountain sickness (AMS) and non-acute mountain sickness (Non-AMS) groups. (A) Comparisons of all microRNAs in microarray analysis of RNA isolated from plasma of AMS and Non-AMS groups. The volcano plot displays the relationship between fold-change and significance using a scatter plot view. The red points in the plot represent the differentially expressed microRNAs with statistical significance. (B) Results of the quantitative reverse-transcription polymerase chain reaction of the miR-369-3p, miR-449b-3p, miR-136-3p, and miR-4791 expression (AMS, n = 41; Non-AMS, n = 46).