Table 3.
Receiver operating characteristic curves of single-plasma microRNAs.
| AUC | 95% CI | P-values | OR per SD | 95% CI | Cut off | Sensitivity (%) | 95% CI | Specificity (%) | 95% CI | LR+ | LR− | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AMS vs. Non-AMS | ||||||||||||
| miR-369-3p | 0.859 | 0.783–0.935 | <0.001 | 62.586 | 8.032–487.699 | >0.038 | 0.95 | 0.83–0.99 | 0.65 | 0.50–0.79 | 2.73 | 0.07 |
| miR-449b-3p | 0.847 | 0.765–0.929 | <0.001 | 8.659 | 3.311–22.648 | >29.602 | 0.71 | 0.54–0.84 | 0.87 | 0.74–0.95 | 5.42 | 0.33 |
| miR-136-3p | 0.724 | 0.617–0.831 | <0.001 | 4.874 | 1.740–13.433 | >0.045 | 0.54 | 0.37–0.69 | 0.83 | 0.69–0.92 | 3.08 | 0.56 |
| miR-4791 | 0.766 | 0.666–0.867 | <0.001 | 7.130 | 2.409–21.104 | >0.091 | 0.73 | 0.57–0.86 | 0.70 | 0.54–0.82 | 2.40 | 0.39 |
AUC, area under curve; CI, confidence interval; LR+, positive likelihood ratio; LR–, negative likelihood ratio; OR per SD, odds ratio per standard deviation; AMS, acute mountain sickness.