Table 4.

Assessment of MGST1 SNPs (n=36) and risk of BE^#

	SNP	Chr	Position	Allelesa	Controls		BE cases		ORc	95% CI	P	qd
					N	MAFb	N	MAFb
1	rs4149203	12	16514921	T/C	3203	0.308	3288	0.346	1.16	(1.08–1.26)	0.0001	0.001
2	rs3852575	12	16516260	T/C	3203	0.304	3288	0.34	1.16	(1.08–1.25)	0.0001	0.001
3	rs7312090	12	16515945	T/C	3203	0.304	3288	0.34	1.16	(1.07–1.25)	0.0002	0.001
4	rs4149204	12	16515062	C/T	3203	0.307	3288	0.342	1.16	(1.07–1.25)	0.0002	0.001
5	rs4149207	12	16517491	T/C	3203	0.306	3288	0.338	1.14	(1.06–1.23)	0.0008	0.005
6	rs4149208	12	16517581	T/C	3203	0.306	3288	0.338	1.14	(1.06–1.23)	0.0008	0.005
7	rs3759207	12	16516710	C/T	3203	0.31	3288	0.34	1.14	(1.05–1.23)	0.0012	0.006
8	rs4149195	12	16512128	G/A	3203	0.109	3288	0.125	1.20	(1.07–1.35)	0.0013	0.006
9	rs2239676	12	16500448	G/C	3203	0.096	3288	0.113	1.19	(1.06–1.34)	0.0033	0.013
10	rs4149187	12	16500071	G/C	3203	0.098	3288	0.114	1.18	(1.05–1.32)	0.0061	0.022
11	rs2239677	12	16500680	A/G	3203	0.021	3288	0.027	1.38	(1.09–1.75)	0.0077	0.025
12	rs2239675	12	16500265	G/A	3203	0.172	3288	0.187	1.12	(1.02–1.23)	0.0172	0.049
13	rs4149186	12	16498700	C/A	3203	0.215	3288	0.235	1.11	(1.02–1.21)	0.0179	0.049
14	rs2975138	12	16501551	A/G	3203	0.237	3288	0.256	1.10	(1.02–1.20)	0.0192	0.049

^#Results for n=14 SNPs satisfying FDR q<0.05,

^aMinor/major alleles,

^bMinor allele frequency,

^cOdds ratio, adjusted for age, sex, PC_1,AIM-PC_4,AIM using additive model (per-allele),

^dFalse discovery rate (FDR)