[Table/Fig-4]:
Prior antibiotic therapies given to patients before admitting to ICU.
| Antibiotic Class | AAE Group N (%) |
Meropenem Group N (%) |
|---|---|---|
| Penicillins | 16 (30.76) | 23 (36.50) |
| 3rd gen cephalosporins | 14 (26.92) | 19 (30.15) |
| 4th gen cephalosporins | 09 (17.30) | 07 (11.11) |
| Carbapenems | 29 (55.76) | 37 (58.73) |
| Quinolones | 12 (23.07) | 16 (25.39) |
| Aminoglycosides | 07 (13.46) | 06 (09.52) |
| Penicillin + β lactamase inhibitor | 24 (46.15) | 31 (49.20) |
| Cephalosporins + Aminoglycosides | 20 (38.46) | 27 (42.85) |
| Carbapenms + Aminoglycosides | 38 (73.07) | 41 (65.07) |
| Penicillin + β lactamase inhibitor + Aminoglycosides | 28 (53.84) | 25 (39.68) |
Note – Antibiotics of different classes used.
Penicillins- Amoxicillin, Piperacillin; 3rd gen cephalosporins - Ceftriaxone, Cefoperazone, Ceftazidime; 4th gen cephalosporins – cefepime; Carbapenems – Meropenem, Imipenem, Ertapenem; Quinolones – Ciprofloxacin, Ofloxacin, Levofloxacin; Aminoglycosides - Amikacin, Penicillin + β lactamase inhibitor – Amoxicillin + Clavulanate, Piperacillin + Tazobactam; Cephalosporins + Aminoglycosides - ceftriaxone + Amikacin, Cefoperazone + Amikacin; Carbapenems + Aminoglycosides – Ertapenem + Amikacin, Imipenem + Amikacin, Meropenem + Amikacin; Penicillin + β lactamase inhibitor + Aminoglycosides - Piperacillin + Tazobactam+ Amikacin