[Table/Fig-4]:
Mean arterial pressure, heart rate and stroke volume with time compared using ANOVA (CPB- cardiopulmonary bypass, SD- standard deviation, CI- confidence interval).
| Parameter | Time (post CPB) | Dobutamine | Levosimendan | Milrinone | p-value | |||
|---|---|---|---|---|---|---|---|---|
| Mean (SD) | 95 % CI | Mean (SD) | 95 % CI | Mean (SD) | 95 % CI | |||
| Mean Arterial Pressure (mmHg) |
1 minute | 45.5 (14.97) | 38.49 – 52.51 | 43.35 (12.0) | 37.72-48.97 | 43.45 (11.59) | 38.02-48.87 | 0.839 |
| 5 minute | 48.85 (15.24) | 41.71 – 55.98 | 45.0 (12.10) | 39.33-50.66 | 46.15 (13.75) | 39.71– 52.58 | 0.663 | |
| 10 minute | 64.0 (15.51) | 56.74 – 71.26 | 55.35 (17.34) | 47.23-63.46 | 53.15 (14.09) | 46.55– 59.74 | 0.078 | |
| 20 minute | 72.05 (13.24) | 65.85 – 78.25 | 60.40 (20.03) | 51.02-69.77 | 57.0 (13.07) | 50.88-63.11 | 0.010 | |
| 30 minute | 76.9 (14.26) | 70.22 – 83.57 | 63.90 (13.01) | 57.81-69.98 | 59.2 (13.4) | 52.92– 65.47 | 0.0004 | |
| Heart Rate (beats per minute) | 1 minute | 62.47 (29.55) | 48.22– 76.72 | 74.70 (26.62) | 62.23-87.16 | 62.5 (24.62) | 50.97 – 74.02 | 0.219 |
| 5 minute | 66.45 (29.76) | 52.52– 80.37 | 74.45 (26.45) | 62.07-86.82 | 66.35 (24.37) | 54.94 – 77.75 | 0.551 | |
| 10 minute | 71.7 (33.54) | 55.99– 87.40 | 81.15 (18.68) | 72.40-89.89 | 68.8 (24.28) | 57.43 – 80.16 | 0.305 | |
| 20 minute | 79.35 (29.36) | 65.60– 93.09 | 83.35 (17.65) | 75.08-91.61 | 75.95 (21.67) | 65.80 – 86.09 | 0.606 | |
| 30 minute | 87.9 (27.01) | 75.25– 100.5 | 83.45 (15.93) | 75.99-90.90 | 79.85 (19.22) | 70.85 – 88.84 | 0.490 | |
| Stroke Volume (milliliters) | 1 minute | 32.3 (15.74) | 24.93-39.67 | 27.15 (8.02) | 23.39-30.90 | 25.3 (11.85) | 19.75 – 30.84 | 0.184 |
| 5 minute | 54.9 (26.13) | 42.66-67.13 | 48.5 (14.98) | 41.48-55.51 | 40.9 (15.80) | 33.50 – 48.29 | 0.087 | |
| 10 minute | 62.3 (19.91) | 52.97-71.62 | 49.15 (13.44) | 42.85-55.44 | 43.35 (15.19) | 36.24 – 50.46 | 0.002 | |
| 20 minute | 62.05(23.15) | 51.21-72.88 | 52.4 (13.39) | 46.13-58.66 | 43.75 (12.32) | 37.98 – 49.51 | 0.005 | |
| 30 minute | 65.5 (15.20) | 58.38-72.61 | 62.55 (15.58) | 55.25-69.84 | 50.95 (15.94) | 43.48 – 58.41 | 0.011 | |