TABLE 2 .
Comparison of single-nucleotide polymorphism characteristics of Plasmodium vivax sequences after selective whole-genome amplification (SWGA) and leukocyte filtrationa
| Sample preparation method | SNP characteristic |
Nonsynonymous-to-synonymous ratio (SNP effect) | ||||
|---|---|---|---|---|---|---|
| Transition/transversion ratio | No. (%): |
SNPs per base | ||||
| Exonic | Intronic | Intergenic | ||||
| SWGA | 1.41 | 20,865 (40) | 3,714 (7) | 25,178 (49) | 0.002 | 1.63 |
| Leukocyte filtration | 1.36 | 18,365 (40) | 3,029 (7) | 23,157 (50) | 0.002 | 1.74 |
a
Samples for SWGA were obtained from Iquitos, Peru, and samples for leukocyte filtration were from a previously published study done in Madre de Dios, Peru (10).