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. 2017 Feb 1;8:14295. doi: 10.1038/ncomms14295

Figure 3. Barr2 deficiency does not affect β-cell Kv and KATP channel currents.

Figure 3

(a) Representative Kv current traces from a control β-cell during 10 mV voltage steps from −70 to 70 mV. (b) Representative Kv current traces from a barr2-deficient (KO) β-cell during 10 mV voltage steps from −70 to 70 mV. (c) Summary of β-cell Kv currents recorded from control and KO β-cells at the indicated voltages and following inhibition with TEA (10 mM). Data are given as means±s.e.m. (d) KATP current recordings (induced by removal of intracellular ATP) from control and barr2-deficient (KO) β-cells at the indicated voltages and following inhibition with tolbutamide (Tolbut; 200 μM). Data are presented as means±s.e.m.