Table 3. S. aureus gene expression during infection of 4-APP-treated and MyD88-deficient C57BL/6 mice.
| Locus tag | Gene symbol | Description | Relative fold change in 4-APP-treated to vehicle-treated C57BL/6 mice (mean (s.e.)) | Relative fold change in MyD88-deficient to wild type C57BL/6 mice (mean (s.e.)) |
|---|---|---|---|---|
| SAOUHSC_02265 | agrA | Accessory gene regulator protein A | −1.60 (0.22) | −1.62 (0.5) |
| SAOUHSC_02566 | sarR | Accessory regulator R | −1.83 (0.22) | −1.23 (0.09) |
| SAOUHSC_01121 | hla | Alpha-hemolysin | −3.32 (1.56) | −18.06 (0.16) |
| SAOUHSC_02971 | aur | Zinc metalloproteinase aureolysin | −2.31 (0.96) | −2.59 (0.75) |
| SAOUHSC_00988 | sspA | Glutamyl endopeptidase | −2.19 (0.01) | −2.32 (0.46) |
| SAOUHSC_00561 | vraX | Protein VraX | −3.91 (2.76) | 1.11 (0.04) |
| SAOUHSC_00436 | gltD | Glutamate synthase subunit beta | −2.41 (1.11) | −6.03 (1.66) |
| SAOUHSC_01803 | aapA | D-serine/D-alanine/glycine transporter | 1.21 (2.32) | 1.69 (0.29) |
| RNAIII | Regulatory RNA | −1.80 (0.53) | −2.52 (0.08) |
Level of expression of a subset of genes by S. aureus during infection of 4-APP-treated compared with vehicle-treated C57BL/6, respectively MyD88-deficient compared with wild-type C57BL/6 mice determined by quantitative reverse transcription–PCR (qRT–PCR).