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. 2017 Feb 8;7:42030. doi: 10.1038/srep42030

Table 1. Clinical features of the elderly participants.

Clinical features Negative (n = 23) Trace to 1+ (n = 77) 2+ to higher (n = 36) P1 value Positive (n = 113) P2 value
Demographic profiles
 Age (years) 79.1 ± 9.9 81.3 ± 8.1 80.4 ± 7.2 0.52 80.1 ± 7.8 0.31
 Gender (male %) 10 (43) 38 (49) 20 (56) 0.66 58 (51) 0.5
Comorbidities (%)
 Diabetes mellitus 1 (4) 33 (43) 19 (53) <0.01 52 (46) <0.01
 Hypertension 10 (43) 47 (61) 21 (58) 0.33 68 (60) 0.14
 Cirrhosis 2 (9) 4 (5) 2 (6) 0.82 6 (5) 0.53
 Coronary artery disease 2 (9) 3 (4) 6 (17) 0.07 9 (8) 0.91
 Old myocardial infarction 0 (0) 1 (1) 0 (0) 0.69 1 (1) 0.65
 Heart failure 2 (9) 16 (21) 5 (14) 0.35 21 (19) 0.25
 Peripheral vascular disease 0 (0) 9 (12) 0 (0) 0.02 9 (8) 0.16
 Chronic obstructive pulmonary disease 3 (13) 8 (10) 4 (11) 0.94 12 (11) 0.74
 Chronic kidney disease 0 (0) 13 (17) 13 (36) <0.01 26 (23) 0.01
 Rheumatologic disorders 0 (0) 4 (5) 0 (0) 0.21 4 (4) 0.36
 Malignancy 5 (22) 21 (27) 9 (25) 0.86 30 (27) 0.63
 Peptic ulcer disease 2 (9) 4 (5) 6 (17) 0.14 10 (9) 0.98
 Old stroke 4 (17) 18 (23) 6 (17) 0.66 24 (21) 0.68
 Dementia or Parkinsonism 0 (0) 15 (19) 4 (11) 0.06 19 (17) 0.03
Charlson Comorbidity Index 6.2 ± 1.9 7.9 ± 2.4 8 ± 2.2 <0.01 7.9 ± 2.4 <0.01
Vital signs on admission
 Systolic blood pressure (mmHg) 141.7 ± 44.8 136.4 ± 36.1 130 ± 39.7 0.49 134.3 ± 37.2 0.41
 Diastolic blood pressure (mmHg) 80.1 ± 24.3 74 ± 19.6 72.7 ± 20.8 0.37 73.6 ± 19.9 0.17
 Heart rate (/minute) 93.7 ± 16.8 98.9 ± 21.2 93.9 ± 22.3 0.38 97.3 ± 21.6 0.45
Laboratory parameters on admission
 Leukocyte count (K/μL) 9.8 ± 6.2 11.7 ± 5.8 15.1 ± 6.7 <0.01 12.8 ± 6.3 0.04
 Hemoglobin (mg/dL) 11.2 ± 2.5 12.6 ± 11.5 10.5 ± 2.7 0.49 11.9 ± 9.6 0.74
 Platelet count (K/μL) 228 ± 117 232 ± 95 208 ± 110 0.51 225 ± 100 0.88
 Serum creatinine (mg/dL) 0.8 ± 0.3 1.5 ± 1.5 2.3 ± 1.8 0.01 1.8 ± 1.6 0.01
 Serum sodium (meq/L) 134 ± 4 132 ± 6.9 134 ± 7.8 0.36 133 ± 7.2 0.59
 Serum potassium (meq/L) 4.6 ± 2.1 4.5 ± 1.1 4.6 ± 1 0.09 4.5 ± 1.1 0.33

Data are expressed as mean ± standard deviation for continuous variables, and number (percentage) for categorical variables.

P1: comparison between participants with different severity of proteinuria.

P2: comparison between participants with and without proteinuria.