Fig. 3.

The results of a longitudinal analysis using a linear mixed model demonstrating the reduction of the PASI score for the combination therapy and monotherapy groups from baseline up to week 48. All observations were made in a 4-week period separated into two groups; the medians per group per time are shown in the graph. We used log-transformed PASI in the regression model to achieve changes to be relative. This is consistent with presenting medians at the original scale.