Table 2.
Baseline Demographic Characteristics of the Study Groups (Post Match)
Baseline characteristics | Intervention (n = 72,410) | Control (n = 72,410) | P value | Standardized difference (¥) |
---|---|---|---|---|
Age at index (years) | ||||
Mean (Standard deviation) | 47.1 (13.3) | 45.7 (13.5) | <.0001 | 0.107 |
95% Confidence interval | [47.0–47.2] | [45.6–45.8] | ||
Sex at index: n (%) | ||||
Male | 29,816 (41.2%) | 29,133 (40.2%) | 0.0003 | 0.019 |
Health plan type at index: n (%) | ||||
Health maintenance organization | 4109 (5.7%) | 1589 (2.2%) | <.0001 | 0.180 |
Preferred provider organization | 63,660 (87.9%) | 67,870 (93.7%) | <.0001 | −0.202 |
All others | 4641 (6.4%) | 2951 (4.1%) | <.0001 | 0.105 |
Primary payer type at index: n (%) | ||||
Commercial | 41,165 (56.8%) | 40,085 (55.4%) | <.0001 | 0.030 |
Medicaid | 574 (0.8%) | 774 (1.1%) | <.0001 | −0.029 |
Medicare | 528 (0.7%) | 131 (0.2%) | <.0001 | 0.082 |
Self-Insured | 30,143 (41.6%) | 31,420 (43.4%) | <.0001 | −0.036 |
Comorbidities: n (%) | ||||
Diabetes mellitus | 7677 (10.6%) | 4804 (6.6%) | <.0001 | 0.142 |
Dyslipidemia | 19,250 (26.6%) | 15,175 (21%) | <.0001 | 0.132 |
Hypertension | 21,973 (30.3%) | 17,856 (24.7%) | <.0001 | 0.128 |
Thyroid disease | 6351 (8.8%) | 4154 (5.7%) | <.0001 | 0.117 |
Mean Charlson comorbidity index score | 0.52 | 0.40 | <.0001 | 0.119 |
Patients with ≥1 emergency room visit | 11,773 (16.3%) | 14,678 (20.3%) | <.0001 | −0.104 |
Mean total number of prescriptions | 11.97 | 10.33 | <.0001 | 0.156 |
Mean number of unique drug classes for prescriptions filled | 5.64 | 5.14 | <.0001 | 0.135 |
Mean 30-day adjusted fill rate | 13.06 | 11.01 | <.0001 | 0.161 |
Mean generic dispensing rate | 0.76 | 0.80 | <.0001 | −0.138 |
¥: Standardized differences were used to assess balance between groups across variables. Balance was determined for differences ≤0.1.