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. Author manuscript; available in PMC: 2017 Feb 8.
Published in final edited form as: Clin Cancer Res. 2015 Sep 15;22(2):470–478. doi: 10.1158/1078-0432.CCR-15-0715

Figure 1.

Figure 1

Representative staining patterns of formalin-fixed, paraffin-embedded primary ICC lesions with CD8- (A and B) and CD4- (C and D) specific mAbs in the fibrous septa (A and C) and tumor lobules (B and D) of ICC lesions. E–H, representative staining patterns of formalin-fixed, paraffin-embedded primary ICC lesions with HLA class I antigen-specific mAbs. Tumor tissue sections were IHC stained with a pool of mouse HLA-A–specific mAb HCA2 and HLA-B/C-specific mAb HC10 (ratio, 1:1). The staining with HLA class I antigen–specific mAbs was scored as negative (E), heterogeneous (F), and positive (G). Representative staining of fibrous septa of ICC lesion with HLA class I antigen–specific mAbs is shown (H). Magnification is indicated.