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. 2017 Feb 7;13:41. doi: 10.1186/s12917-017-0950-6

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Lung photomicrography. a Well-circumscribed cavitations areas of granulomatous pneumonia associated pleomorphic, yeast structures with mucinous capsule of variable thickness which show clear and refractile halo (HE stain, bar = 25 μm). b Yeast in details with oval to round, and 5–20 μm in diameter organism’s structure which capsule (carminophilic) stain in red inside of cavitations areas (cryptococcomas). (Mayer’s Mucicarmin stain, bar = 50 μm). c Cryptococcal antigen was detected by immunohistochemistry using anti-Cryptococcus polyclonal antibody, 1:50,000 diluted. Positive yeast structures stained in strong brown for Cryptococcus spp. PictureMax Kit™, DAB stain, bar = 25 μm