Fig. 2.

OxLDL influence JAB1 protein expression and foam cell formation in differentiated human MΦ. PMA-differentiated human U937 MΦ were incubated (4 h) with medium alone (= control) or oxLDL (50, 100, 200 μg/ml). The JAB1 and α-tubulin protein levels were determined using western blot analysis and quantified by ImageJ. Expression was normalized against α-tubulin. Bars represent mean ± SEM of 4 independent experiments. *p < 0.05 significance vs. control