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Genotypic and allelic frequency of MUTYH-437 (rs3219463) genetic polymorphism in the RA patients and controls
| RA patient | Control | OR (95% CI) | p value | |
|---|---|---|---|---|
| MUTYH-437 (rs3219463) | n = 368 (%) | n = 364 (%) | ||
| AA | 54 (14.7) | 47 (12.9) | 1.80 (1.14-2.84) | 6E-06 * |
| AG | 204 (55.4) | 145 (39.8) | 2.20 (1.60-3.03) | |
| GG | 110 (29.9) | 172 (47.3) | Ref | |
| Allelic frequency | ||||
| Allele A | 312 (42.4) | 239 (32.8) | 1.51 (1.22-1.86) | 0.0002 * |
| Allele G | 424 (57.6) | 489 (67.2) | Ref | |
CI confidence interval, OR odds ratio
* Statistically significant
