Table 3.

Classification of functional capacity and measurement of joint changes in RA patients

	RA patients		Chi-Square a p value	Fisher’s Exact test a p value
	Genotype at rs3219463
	G carrier - n (%)	AA - n (%)
RA Diagnosis class
I	88 (75.2)	13 (56.5)	0.315	0.199
II	19 (16.2)	6 (26.1)
III	8 (6.8)	3 (13.0)
IV	2 (1.7)	1 (4.3)
	RA patients		T-Test a p value	Mann–Whitney U test a p value
	Genotype at rs3219463
	G carrier - n (mean ± SD)	AA - n (mean ± SD)
MUTYH serum level b	27 (20.98 ± 16.51)	13 (23.07 ± 17.16)	0.714	0.593
Joint pain	135 (31.93 ± 24.33)	28 (45.89 ± 25.46)	0.007 *	0.006 *
Joint stiffness	102 (0.62 ± 0.97)	19 (0.58 ± 0.72)	0.871	0.540
SJC 66 b	142 (1.96 ± 2.69)	26 (2.81 ± 3.18)	0.156	0.250
TJC 68 b	142 (3.83 ± 4.07)	26 (6.69 ± 7.06)	0.055	0.075
DAS 28	133 (3.88 ± 1.2)	25 (4.63 ± 1.23)	0.005 *	0.003 *
PtGA b	135 (39.65 ± 26.72)	27 (50.48 ± 27.82)	0.058	0.052
PrGA b	142 (23.73 ± 17.73)	27 (32.78 ± 23.38)	0.065	0.078

^a Nonparametric test

^b Mean value is lower in the G carrier / RA-non-risk-associated but data does not reach statistical significance

* Statistically significant