Table 1.

Characteristics of included studies (eight study populations; 13 articles)

Study region	Data source(s)	Study years	Study population	Number	Mean age (years)	Men (%)	Follow-up (years)	Reference
Denmark	National Prescription Register, National Patient Register, Central Population Register	1997–2006	Individuals aged ≥30 years with first MI and without prior diabetes	77,147	70	61	Up to 5	Norgaard et al. 2010 [19]
Spain	Single center Coronary Care Unit Registry	1988–2008	Individuals aged ≥75 years with first STEMI	1393	81	49	1 and 5	Viana-Tejedor et al. 2015 [23]
Sweden	National Hospital Discharge Register, National Cause of Death Registry	1993–2004	Individuals admitted for first MI (no prior HF or CAD)	175,216	69	64	3	Shafazand et al. 2011 [21]
	RIKS-HIA	1996–2007	Individuals with first STEMI	61,238	70	65	Up to 15	Jernberg et al. 2011 [13]
	National Inpatient Register	1987–2006	Individuals with first MI aged 25–54 years	37,276	NR	81	4	Nielsen et al. 2014 [18]
	Northern Sweden MONICA MI Registry, Swedish National Cause of Death Registry	1985–2006	Individuals with first MI	8630	56	78	Median: 7.1	Isaksson et al. 2011 [12]
Netherlands	Thoraxcenter ICCU, Erasmus University Medical Center	1985–2008	Individuals hospitalized for MI
			With NSTEMIa	7614	63	70	3	Nauta et al. 2011 [15]
			With STEMIa	6820	61	75	3	Nauta et al. 2011 [15]
							10	Snelder et al. 2013 [22]
			With renal impairmentb	8632			Up to 20	Nauta et al. 2013 [17]
			With diabetesa	2015			Up to 20	Nauta et al. 2012 [14]
			With elevated blood glucosec	4671			Up to 20	Deckers et al. 2013 [11]
			Womena	4028			Up to 20	Nauta et al. 2012 [16]
United Kingdom	CALIBER (CPRD, MINAP, HES, and ONS)	2000–2010	Individuals with stable angina, other CHD, unstable angina, STEMI, NSTEMI, or unclassified MI	102,023 (STEMI: 4700; NSTEMI: 6818; unclassified MI: 9620)	STEMI: 66; NSTEMI: 72; unclassified MI: 69	STEMI: 72; NSTEMI: 63; unclassified MI: 65	Mean: 4.4d	Rapsomaniki et al. 2014 [20]

CAD coronary artery disease, CALIBER CArdiovascular disease research using LInked BEspoke studies and electronic health Records, CHD coronary heart disease, CPRD Clinical Practice Research Datalink, HES Hospital Episodes Statistics, HF heart failure, ICCU intensive coronary care unit, MI myocardial infarction, MINAP Myocardial Ischaemia National Audit Project registry, MONICA MONItoring trends and determinants in CArdiovascular disease, NR not reported, NSTEMI non-ST-elevation myocardial infarction, ONS Office for National Statistics, RIKS-HIA Register of Information and Knowledge about Swedish Heart Intensive care Admissions, STEMI ST-elevation myocardial infarction

^aOf 14,434 individuals hospitalized for MI

^bOf 12,087 individuals hospitalized for MI

^cOf 11,324 individuals hospitalized for MI

^dFollow-up started 6 months after the event