Table 1.

Summary of treatment modalities for osteoporosis

Treatment modalities	Drug class	Medications
Lifestyle modifications	Nutritional supplements Physical activity Smoking cessation Limited alcohol & caffeine consumption	Calcium & Vitamin D
Pharmacological agents (antiresorptive drugs)	BPs	Alendronate, Risedronate, Ibandronate, Zoledronic acid, Clodronate, Minodronate, Pamidronate, Etidronate, Tiludronate
	RANKL antibody	Denosumab
	Estrogen replacement	Estrogen conjugate
	SERMs	Raloxifene, Tamoxifene, Lasofoxifene, Bazedoxifene, Arzoxifene
	Calcitonin	Calcitonin
	Cathepsin k inhibitors	Odanacatib, Balicatib, ONO-5334
	Strontium ranelate	Strontium
Pharmacological agents (anabolic drugs)	PTH peptides Anti-sclerostin antibodies	Teriparatide, PTH 1-84 Romosozumb, Blosozumab, BPS804

Legend: BPs Bisphosphonates, SERMs selective estrogen receptor modulator