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. 2016 Dec 16;9(2):240–256. doi: 10.1080/19420862.2016.1270492

Table 2.

Equilibrium KD (nM) determined by BIAcore for the binding to human FcRn for Bs4Ab-VA and for the anti-VEGF and anti-Ang2 antibodies.

Human FcRn anti-VEGF anti-Ang2 Bs4Ab-VA
pH 6 840 800 680
pH 7.4/6 Negative Negative Negative

“Negative” denotes that FcRn binding at pH 7.4 relative to pH 6 was negligible (i.e., < 1%).