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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Free Radic Biol Med. 2016 Mar 30;96:13–21. doi: 10.1016/j.freeradbiomed.2016.03.032

Fig. 3.

Fig. 3

Effect of a Western diet on hepatic glutathione redox ratio in LDLR−/− mice. Hepatic content of reduced glutathione (GSH) (Panel A), total glutathione (GSH+GSSGR) (presented in Table 1) was analyzed by mass spectrometry as described in Section 2. Hepatic oxidized glutathione (GSSR) content (Panel B) was calculated as the difference of total and reduced glutathione. Glutathione redox ratio (GSH/GSSR) in the liver (Panel C) was calculated based on hepatic content of reduced and oxidized glutathione. Data are presented as mean ± SD (n = 6/group). *P < 0.05.