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. 2016 Dec 22;18(1):1. doi: 10.3390/ijms18010001

Figure 5.

Figure 5

CD11c+ CD8+ T cells mainly constitute the population of CD8 T cells expressing the mRNA of cytotoxin related factors in obstructed kidney. (A) CD11c− CD8+ T cells and CD11c+ CD8+ T cells in kidney at UUO 5 days were separated through cell sorting after incubation of the total number of cells in antibody cocktail (anti-CD45, CD3e, CD8a, and CD11c). CD11c isotype control group: incubated in antibody cocktail (anti-CD45, CD3e, and CD8a and an isotype control of CD11c antibody); (B–E) mRNA levels of cytotoxin related factors (PRE-1, GZMA, GZMB, and FASL) as determined in those CD11c− CD8+ T cells or CD11c+ CD8+ T cells by quantitative RT-PCR (* p < 0.05 vs. CD11c− CD8+ T cells; n = 5).