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Organ accumulation of IS in BNx rats. Organ accumulation of IS were determined in sham-operated rats (sham), BNx rats with (BNx + AST-120) or without (BNx) oral administration of AST-120 (2.5 g/kg) at 48 h. Each column represents the mean ± SD for seven to 10 rats in each group. ** p < 0.01 versus sham; ## p < 0.01 versus BNx.
