Figure 7.
Schematic representation of the modulation of AD-related transcripts by CBD in GMSCs. CBD inhibited the transcription of the main kinases involved in tau phosphorylation (GSK3β and CDK5) and the enzymes involved in Aβ processing. In parallel, CBD potentiates the HSP70/HSP90 and the ubiquitin machineries to promote Aβ and p-tau degradation.