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. 2017 Jan 1;18(1):73. doi: 10.3390/ijms18010073

Figure 4.

Figure 4

ZC increases survival of BrdU-positive cells in the late phase of STZ-induced diabetic rats. (A) Experimental procedure in the late phase of STZ-induced diabetic rats; (B) Bright field photomicrographs show surviving newborn cells. In the late phase, the STZ-injected group showed a significant decrease of BrdU (+) cells. However, ZC treatment by gavage for six weeks after STZ-induced hyperglycemia significantly increased BrdU (+) cells. Scale bar = 100 µm; (C) Bar graph represents BrdU-positive cells in the SGZ/GCL. Data are means ± SE, n = 6–8 from each group. * p < 0.05, versus sham group; # p < 0.05, versus vehicle-treated STZ group.